Education:
D.Phil in Organopalladium Catalysis involving NMR, GC/MS, LC/MS studies
University of Oxford, UK (2009)
Short Biography:
2000 Oracle Database Management Programme Certification
Hamdard University.
2001-2002 Graduate Engineers Training Programme
Dawood Hercules Chemicals Ltd.
2002 Nuclear Orientation Course
Pakistan Institute of Engineering and Applied Sciences.
2005 Building a Business course based around Science Enterpreneurship
Oxford Science Enterprise Centre, Said Business School, University of Oxford, UK.
2008 Academic Visitor
The Scripps Research Institute, California USA.
Positions Held:
2002-2007 Scientific Officer
2007-present Senior Scientist
Research Interests:
- Applications of catalytic methods especially palladium catalyzed C-C couplings in the synthesis of biologically potent compounds.
- Palladium catalyzed C-H activation studies in the target substrates, important in the synthesis of antiviral and antimicrobial agents.
- Isolation and characterization of natural products’ secondary metabolites for their potential bioactivities, specifically against the microorganisms of indigenous origin.
Publications:
- Rauf, W.; Brown, J. M.: Catalytic amide-mediated methyl transfer from silanes to alkenes in Fujiwara-Moritani oxidative coupling. Angewandte Chemie-International Edition 2008, 47, 4228-4230.
- Rauf, W.; Thompson, A. L.; Brown, J. M.: Comparative catalytic C-H vs. C-Si activation of arenes with Pd complexes directed by urea or amide groups. Chemical Communications 2009, 3874-3876. (Hot Article)
- Rauf, W.; Brown, J. M.: Catalytic Amide-Directed Palladadesilylation-Alkenylation. Synlett 2009, 3103-3106.
- Rauf, W.; Hazari, A.; Gouverneur, V.; Brown, J. M.: Catalytic activation of hydrogen, silicon, and fluorine by transition-metal complexes. Pure and Applied Chemistry 2010, 82, 1415-1428.
- Rauf, W.; Thompson, A. L.; Brown, J. M.: Anilide activation of adjacent C-H bonds in the palladium-catalysed Fujiwara-Moritani reaction. Dalton Transactions 2010, 39, 10414-10421.
- Rauf, W.; Brown, J. M.: Reactive intermediates in catalytic alkenylation; pathways for Mizoroki-Heck, oxidative Heck and Fujiwara-Moritani reactions. Chemical Communications 2013, 49, 8430-8440. (Feature Article)
- Rauf, W.; Brown, J. M.:Palladium-catalysed directed C–H activation by anilides and ureas; water participation in a general base mechanism. Organic and Biomolecular Chemistry 2016, 14, 5251-5257.
- Imran, M.; Fazal-e-Habib.; Tawab, A.; Rauf, W.; Rahman, M.; Khan, Q.M.; Asi M. R., Iqbal, M.: LC–MS/MS based method development for the analysis of florfenicol and its application to estimate relative distribution in various tissues of broiler chicken. Journal of Chromatography B 2017, 1063, 163–173.
- Rauf, W.; Brown, J. M.: Mechanisms for C(sp2)-Si Activation of Aryltrimethylsilyl Groups in Palladium-catalysed Couplings. Organic and Biomolecular Chemistry 2017.
Research Grants:
- Palladium catalyzed C-H activation in tert-amide directed Fujiwara-Mortani reaction Funding Agency: Higher Education Commission, Pakistan.
- Palladium catalyzed C-H activation at C-5 positions of 2-aminothiazole ring Funding Agency: Higher Education Commission, Pakistan
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