Thursday, April 25, 2024
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Dr. Waheed S. Khan

waheedskhan@yahoo.com,waheedskhan@nibge.org


Dy. Chief Scientist
Group Leader of Nanobiotechnology Research Group

Work Phone: 0092-41-9201404 Ext.3293
Fax Phone: 0092-41-9201322
Cell/Direct Phone: 0092-331-5267520
Dr. Waheed S. Khan

Academic Qualification

  • Post Doc. Nanotechnology, 2018, Ningbo Institute of Materials Technology and Engineering (NIMTE)-CNITECH, Chinese Academy of Sciences (CAS), Ningbo City, Zhejiang Province, P. R. China.
  • Ph.D.    Nanotechnology, 2011, School of Materials Science and Engineering, Beijing Institute of Technology, Beijing, P.R. China.
  • M. Phil.  Physics, 2000, Physics Department, Quaid-I-Azam University, Islamabad, Pakistan.
  • M.Sc.     Physics, 1995, Physics Department, Punjab University, Lahore, Pakistan.
  • B.Sc.      1992, Physics, Maths-A & B, (Govt. Gordon College, RWP) Punjab University Lahore, Pakistan

 

Research Interests

  • Synthesis: Chemical Vapour Deposition, Hydrothermal, Solvo-Thermal  Techniques, Bio-Synthesis, Microwave-Assisted Synthesis,  
  • Characterization Techniques: XRD, SEM, EDS, FESEM, TEM, HRTEM, XPS, Raman, SAED, FTIR etc.
  • Properties and Applications: Photocatalytic degradation of organic pollutants, Bio-imaging, Biosensing, Self-Cleaning Surfaces, Antibacterial/Antiviral Activities, Enzyme Immobilization, etc

 

Synthesis of Tungstate based Nanomaterials for Photocatalytic and Biosensing Applications

Various tungstate based nanomaterials such as barium tungstate (BaWO4) , bismuth tungstate (Bi2WO6), zinc tungstate (ZnWO4) etc were synthesized using facile, efficient and cost effective Hydrothermal Technique. These nanomaterials were characterized using high tech facilities like SEM, XRD, EDS, TEM, etc. Later these materials were explored for their potential applications in photocatalytic degradation of harmful compounds, organic dyes, waste materials under artificial light and sunlight.

 

Bismuth tungstate (Bi2WO6) and zinc tungstate (ZnWO4) were further investigated for their detection applications. MWCNTs/Bi2WO6 nanocomposite was used as a sensor coating for the mass-sensitive detection of rifampicin (RIF).

This nanocomposite was employed as a transducer layer for RIF onto the QCM sensor and multiple studies were directed to bring out the sensing characteristics of the material as well as to have a preliminary understanding of the selectivity. The developed sensor showed high sensitivity toward rifampicin, excellent reproducibility and stability. Similarly, one dimensional (1D) nanostructures of ZnWO4 were employed for the detection of a model antibiotic, chloramphenicol. The developed sensor exhibited excellent limit of detection, 0.32 μM and 100%

specificity as compared to its structural and functional analogues such as thiamphenicol and clindamycin. This work can broaden new opportunities for the researchers to explore unconventional nanomaterials bearing unique morphologies and quantum phenomenon for the label-free detection of other bioanalytes.

 

It is necessary to study the possible interactions among various chemical surfaces and analytes before applying them to biological systems. Carbon nanotubes- iron oxide (SPIONs-CNT) nanocomposite was synthesized by using lecithin stabilized superparamagnetic iron oxide nanoparticles (SPIONs) obtained by facile hydrothermal technique. Various characterizations of the obtained nanocomposite were carried out and electrochemical studies were performed further to study the interaction capabilities of the nanocomposite with anti-TB drug Rifampicin. Obtained results by cyclic voltammetric studies of SPIONs-CNT nanocomposite with limit of detection (LOD) of 1.178µM showed the enhanced electrochemical sensitivity and selectivity of anti-tuberculosis (anti-TB) drug Rifampicin (Rif).

 

RESEARCH PROJECTS

 

INTERNATIONAL

  •  Integration of ultrasound and nano technology based approaches for enhancing the therapeutic efficacy of prostate cancer (PKR 10.13M, PI in Pakistan; Dr. Waheed S. Khan and PI in China: Prof. Dr. Zhifei Dai)

 

NATIONAL

  • Olfactory Response and Host Plant Feeding Preferences of Desert Locust to Common Plants in Punjab Province of Pakistan (PKR72M, Funding Agency is HEC (GCF Project), PI= Dr. Shahid Majeed-UAF, Sub-Awardee Dr. Waheed S. Khan,
  • Development of Magnetic Nanoparticles Based Support for the Immobilization of NIBGE-Alpha-amylase Enzyme to Produce Maltose Syrup from Corn Starch (PKR5.4M, Funding Agency is HEC, PI= Dr. Waheed S. Khan, Co-PI= Dr. Hamid Rashid)
  • Synthesis  and  Application  of  Layered  Bismuth  Oxyhalide  based  Nanomaterials  for  Photocatalytic Degradation of Industrial Waste Dyes (PKR3.063M, Funding Agency is HEC, PI= Dr. Waheed S. Khan, Co-PIs= Dr. Mazhar Iqbal, Dr. Sadia Zafar Bajwa)
  • Development of low cost chip based biosensor for the detection of breast tumor (PKR7.16M, Funding Agency is HEC, PI= Dr. Sadia Zafar Bajwa, Co-PI= Dr. Waheed S. Khan)
  • Reinforcement of plastic products by using carbon based Nano-materials for local industrial application (PKR 3.0M, Funding Agency is HEC, PI= Dr. Ghulam Nabi (Univer. of Gujrat), Co-PI= Dr. Waheed S. Khan)
  • Carbon and Transition Metal Oxide Nanomaterials based high performance Supercapacitors (PKR 5.22M, Funding Agency is HEC, PI= Dr. Ghulam Nabi (Univer. Of Gujrat), Co-PI= Dr. Waheed S. Khan)
  • Development of magnetic nanostructure for energy efficient applications based on ultra strong permanent magnet and soft magnet (PKR 3.67M, Funding Agency is HEC, PI= Dr. M.Yasir Rafique (CIIT, Lahore), Co-PI= Dr. Waheed S. Khan)
  • Synthesis of Tungstate based Nanomaterials using Uniform Strategy for Efficient and Low-Cost Photocatalytic Degradation of Toxic Materials (PKR 2.1M, Funding Agency is HEC, PI= Dr. Tariq Mahmood (GCUW, Sialkot), Co-PI= Dr. Waheed S. Khan)
  • Defect Engineering of oxide based nanomaterials for improved photocatalytic performance and environmental applications (PKR 7.4M, Funding Agency is HEC, PI= Dr. Masood ul Hassan (UET, KSK Lahore), Co-PI= Dr. Waheed S. Khan)
  • Development of Lipids Based Nanoparticles for BCS-II anti-cancer drugs with Improved Bioavailability  and More Patient Compliance rate (PKR 2.17M, Funding Agency is HEC, PI= Prof. Dr. Mir Azam Khan (UoM, Malakand KPK), Co-PI= Dr. Waheed S. Khan)
  • Removal of Arsenic From Drinking Water Using Integration of Phytoremediation and Iron Oxide Nanoparticles Imbedded Biochar (PKR 3.97M, Funding Agency is HEC, PI= Dr. Ejaz ul Islam,  Co-PI= Dr. Waheed S. Khan)
  • Development of carbon quantum dots based electrochemical nanobiosensor for selective detection of clinically important biomolecules (PKR 2.31M, Funding Agency is HEC, PI= Dr. RAzium Ali Somro,  Co-PI= Dr. Waheed S. Khan . This project was NOT taken by up by NIBGE owing to leaving of NIBGE by Dr. Razium.)
  • Development of Nanoparticles (NPs) based methods to detect adulterations and authenticity of Basmati Rice (PKR 4.67M, Funding Agency is HEC, PI= Dr. M. Arif ,  Co-PI= Dr. Waheed S. Khan)
  • NOVEL THREAPAUTIC APPROACH OF CAPPED MAGNETIC NANOPARTICLES FOR CANCER TREAMNET VIA HYPERTHERMIA THERAPY (PKR 4.8M, Funding Agency is PSF, PI= Dr. Tariq Munir ,  Co-PI= Dr. Waheed S. Khan)
  • Conversion of PPE Waste into Multipurpose Beneficial Material Using Self Designed Pyrolysis Technique: A Safe Disposal with Trash-To-Treasure Approach (PKR 4.175M, Funding Agency is PSF, PI= Dr. Asma Rehman ,  Co-PI= Dr. Waheed S. Khan)

 

 

Selected Research Publications

 

  1. Concomitant Effect of Quercetin and Its Copper Complex in the Development ofSustained-Release Nanoparticles of Polycaprolactone, Used for the Treatment ofSkin InfectionMolecular Pharmaceutics (ACS) (2023) (Impact Factor 5.364 ) Nasreen Ramzan | Ghulam Abbas | Khalid Mahmood | Mubashir Aziz | Sumaira Rasul |Nadeem Ahmed | Shahid Shah | Muhammad Uzair | Muhammad Usman | WAHEED S.KHAN | Muhammad Hanif | Muhammad Sami Ullah
  2. Characterization of Azadirachta indica synthesized silver nanoparticles and its toxicityagainst Dusky cotton bug, Oxycarenus hyalinipennis Costa (Hemiptera:Lygaeidae) International J. of Tropical Insect Science (Springer) 43 (2023) 463–473 (IF:1.02)Muhammad Javaid | Unsar Naeem-Ullah | WAHEED S. KHAN | Shafqat Saeed | Mirza AbdulQayyum | Muhammad Arslan Khan
  3. Leakage current, electrical properties and density of states extracted usingcorrelated barrier hopping in perovskite layered aurivillius Bi 5 Ti 3 FeO 15nanoparticlesArifa Jamil | I. Rashid | WAHEED S. KHAN | Sadia Zafar Bajwa | Asma Rehman | and M. A.Rafiq
  4. Solution grown multilayered zinc vanadium oxide nanosheets as a new material tobind glutathioneJ. Materials Research and Technology (Elsevier) 17 (2 0 2 2)1 7 7 7- 7 8 5 (ImpactFactor 6.267)Ayesha Taj | Hafsa Maqsood | Rabisa Zia | Adnan Mujahid | Adeel Afzal | Zeeshan Tariq |Faheem K. Butt | WAHEED S. KHAN | Sadia Z. Bajwa 
  5. Biocidal activity of green synthesized silver nanoformulationby Azadirachta indica extract a biorational approach against notoriouscotton pest whitefly, Bemisia tabaci (Homoptera; Aleyrodidae)International J. of Tropical Insect Science (Springer) 42 (2022) 2443–2454 (IF: 1.02)Muhammad Shahid | Unsar NaeemUllah | WAHEED S. KHAN | Shafqat Saeed | Kashif Razzaq
  6. Green synthesis of Ag@CdO nanocomposite and their application towards brilliant greendye degradation from wastewaterJ. Nanostructure in Chemistry (Springer) 12 (2022) 329–341 (Impact Factor 8.00)Khalid Mahmood | Umay Amara | Shahzadi Siddique | Muhammad Usman | Qiaohong Peng |Muhammad Khalid | Ajaz Hussain | Muhammad Ajmal | Adeel Ahmad | Sajjad H. Sumrra |Zheng-Ping Liu | WAHEED S. KHAN | Muhammad Naeem Ashiq
  7. Biofunctionalized nano-antimicrobials - progress, prospects and challengesCurrent Topics in Medicinal Chemistry (Bentham Sci. Pub) 22 (2022) 1046 - 1067 (Impactfactor 3.57)Ata Ullah | Lutfur Rahman | Sabahat Asif | WAHEED S. KHAN | Asma Rehman
  8. Effect of high pressure on structural, electrical, and optical properties of graphene-like zinc oxide (g-ZnO) structureMaterials Science in Semiconductor Processing (Elsevier) 142 (2022) 106465 (IF 4.644)Muhammad Azhar Nazir | Tariq Mahmood | Naeem Akhtar | Kashif Hussain | WAHEED S.KHAN | Muhammad Asad Waqare | Fazal-E Aleem | Aamir Saeed |Muhammad Fareed-Un-NabiSaqi | Jafar Raza
  9. Ultrathin 2D bismuth oxychloride nanosheets as novel catalytic interfaces fordetection of biomoleculesMaterials Science and Engineering B 278 (2022) 115651 (Impact Factor 3.407)Sumaira Younis | Ayesha Taj | Adnan Mujahid | Alireza Ahmadian Yazdi | Jie Xu | Haq NawazBhatti | WAHEED S. KHAN | Sadia Z. Bajwa
  10. Fabrication of bismuth molybdenum oxide nanoparticles as a dual interface for
    photocatalysis and biosensingApplied Nanoscience (Springer) 12 (2022) 2563–2577 (Impact Factor 3.869)Zeeshan Akmal |Ayesha Taj |Ahmed Madni |Raja Adil Sarfraz | M. Zubair Iqbal | MuhammadAfzal |Arshad Mahmood | Khalid Mahmood |Sadia Z. Bajwa | WAHEED S. KHAN |
  11. Synthesis of graphitic carbon nitride nanosheetslayered imprintedpolymer system as a nanointerface for detection of chloramphenicolApplied Nanoscience (Springer) (2022) 139–150 (Impact Factor 3.869) Aysha Shaheen | Ayesha Taj | Farwah Jamel | Muhammad Ali Tahir | Adnan Mujahid | FaheemK. Butt | WAHEED S. KHAN | Sadia Z. Bajwa
  12. Synthesis and toxicity assessment of environment friendly high yield ceria nanoparticles for biosafetyJ. of Environmental Chemical Engineering (Elsevier) 10 (2022) 107029 (IF: 7.968)M. Usama Marghoob | Aasma Naurin | Ali Raza | WAHEED S. KHAN | Mehwish Iftikhar |Farooq Sher

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