Friday, April 19, 2024
Profile

Dr. Abdul Tawab (Principal Scientist)

atawab11@gmail.com, atawab1@yahoo.com





Work Phone: (041) 9201316-20Ext 3283,3291
Fax Phone: (+92 41) 9201472
Dr. Abdul Tawab (Principal Scientist)

Qualification: 

  • Ph.D (Biotechnology): 2021, from NIBGE-C, Pakistan Institute of Engineering and Applied Sciences (PIEAS), Islamabad, Pakistan
  • M.Sc (Chemistry): 2004, from the University of Karachi, Karachi, Pakistan
  • B.Sc (Pre-Medical): 2000, from the University of Peshawar, Peshawar, Pakistan 

 

 Research Interests:

  • Isolation, screening and characterization of Gram-negative bacteria especially Pasteurella multocida and Salmonella Typhe and other enteric pathogenic microbes.
  • Extraction, purification and characterization of extracellular moieties, especially lipopolysaccharides, capsular and other biotoxins of these pathogenic microbes.
  • Analysis and structural elucidation of exo/endotoxins especially lipopolysaccharides (LPS) and capsular moieties.
  • Exploring the role of biotoxins in various metabolic disorders, disease development and progression, especially vitamin-D deficiency and cancer etc.
  • Analytical method development for biomolecules, metabolites, toxins in food, glycolipids, peptides / proteins, synthetic molecules and veterinary drugs residues, using various hi-tech analytical techniques e.g., LC-MS/MS, GC-MS/MS, Capillary Electrophoresis and NMR etc.

 

Research Publications: 

  1. Zulfiqar Raza, Maha Shabbir, Muhammad Irfan Majeed, and Abdul Tawab. (2023). Development of citric acid grafted graphene oxide nanosheets as nanocatalyst in the synthesis of an imidazole derivative. Inorganic and Nano-metal Chemistry. Doi.org/10.1080/24701556.2023.2271449
  2. Muhammad Wasim, Haq Nawaz Khan, Abdul Tawab, Fazal e Habib, Mazhar Iqbal, Fazli Rabbi Awan. (2023). High-performance liquid chromatography-based assay optimization for the detection of plasma amino acids for applications in metabolic disorders in developing countries. Separation Science Plus. Doi: 10.1002/sscp.202300119.
  3. Masooma Hammad, Hazrat Ali1, Noor Hassan, Abdul Tawab, Mahwish Salman, Iqra Jawad, Anne de Jong, Claudia Munoz Moreno, Oscar P. Kuipers, Yusra Feroz, Muhammad Hamid Rashid. (2023). Food Safety and Biological Control; Genomic Insights and Antimicrobial Potential of Bacillus velezensis FB2 against Agricultural Fungal Pathogens. Plos One. Doi: 10.1371/journal.pone.0291975
  4. Anam Tariq,Mahwish Salman ,Ghulam Mustafa, Abdul Tawab, Shazia Naheed, Hafsa Naz, Misbah Shahid, Hazrat Ali. (2023). Agonistic antibacterial potential of Loigolactobacillus coryniformis BCH-4 metabolites against selected human pathogenic bacteria: An in vitro and in silico approach. Plos One.  Doi: 10.1371/journal.pone.0289723.
  5. Muhammad Rizwan Javed, Mahwish Salman, Anam Tariq, Abdul Tawab, Muhammad Kashif Zahoor, Shazia Naheed, Misbah Shahid, Anam Ijaz and Hazrat Ali. (2022). The Antibacterial and Larvicidal Potential of Bis-(2-Ethylhexyl) Phthalate from Lactiplantibacillus plantarum. Molecules. 2022, 27(21), 7220; Doi: 10.3390/molecules27217220.
  6. Faiza Shams, Ayesha Azeem, Ammara Shams, Abdul Tawab, Sidra Rehman, Somayya Tariq, Noreen Latief, Bushra Ijaz. (2022). Flavonoid rich extract of Trigonella foenum-graecum leaves ameliorate liver fibrosis. Food Bioscience. 50(A): 102046. Doi: 10.1016/j.fbio.2022.102046.
  7. Syed Asim, Anwar Hussain, Waheed Murad, Muhammad Hamayun, Amjad Iqbal, Hazir Rehman, Abdul Tawab, Muhammad Irshad, Abed Alataway, Ahmed Z. Dewidar, Hosam O. Elansary, In-Jung Lee. (2022). Endophytic Fusarium oxysporum GW controlling weed and an effective biostimulant for wheat growth. Frontiers in Plant Science. 13:922343. Doi: 10.3389/fpls.2022.922343.
  8. Mahwish Salman, Muhammad Rizwan Javed, Hazrat Ali, Ghulam Mustafa, Anam Tariq, Tanzila Sahar, Shazia Naheed, Iqra Gill, Muhammad Abid, Abdul Tawab. (2022). Bioprotection of Zea mays L. from aflatoxigenic Aspergillus flavus by Loigolactobacillus coryniformis BCH-4: Detoxification of Zea mays L. to save its nutritional value. Plos One. 17(8):1-17. Doi: 10.1371/journal.pone.0271269.
  9. T. Tabassum, H. Rahman, A. Tawab, W. Murad, H. Hameed, SAR Shah, K. J. Alzahrani, H. J. Banjer, M. A. Alshiekheid. (2022). Fagonia cretica: Identification of compounds in bioactive gradient high performance liquid chromatography fractions against multidrug resistant human gut pathogens. Tropical Biomedicine. 39(2): 185-190.  Doi: 10.47665/tb.39.2.006.
  10. Samina Anwar, Abdul Qadeer Wahla, Tayyaba Ali, Shazia Khaliq, Asma Imran, Abdul Tawab, Muhammad Afzal, Samina Iqbal. (2022). Biodegradation and Subsequent Toxicity Reduction of Co- contaminants Tribenuron Methyl and Metsulfuron Methyl by a Bacterial Consortium B2R. ACS Omega. 7: 19816 – 19827. Doi: 10.1021/acsomega.2c01583.
  11. Shahzad Murtaza, Naghmana Kausar, Uswa Arshad, Safeer Ahmed, Adina Tatheer, Jawariya Najeeb, Abdul Tawab. (2022). Novel 2-aminobenzohydrazide derivatives, Design, synthesis, anti-Alzheimer evaluation, SAR studies and molecular docking analysis. Journal of Molecular Structure. 1264: 133271. doi.org/10.1016/j.molstruc.2022.133271.
  12. Muhammad Wasim, Haq N. Khan, Hina Ayesha, Mazhar Iqbal, Abdul Tawab, Muhammad Irfan, Warsha Kanhai, Susanna MI Goorden, Lida Stroomer, Gajja Salomons, Frederic M Vaz, Clara DM van Karnebeek, Fazli R Awan. (2022). Identification of three novel pathogenic mutations in cystathionine beta-synthase gene of Pakistani intellectually disabled patients. Journal of Pediatric Endocrinology and Metabolism. DOI: 10.1515/jpem-2021-0508.
  13. Naghmana Kausar, Shahzad Murtaza, Muhammad Nadeem Arshad, Rubina Munir, Rahman Shah Zaib Saleem, Hummera Rafique, Abdul Tawab. (2021). Design, synthesis, structure activity relationship and molecular docking studies of thiophene-2-carboxamide Schiff base derivatives of benzohydrazide as novel acetylcholinesterase and butyrylcholinesterase inhibitors. Journal of Molecular Structure. 1244: 130983. DOI: 10.1016/j.molstruc.2021.130983.
  14. Mahreen Yahya, Maria Ejaz ul Islam, Rasul, Iqra Farooq, Naima Mahreen, Abdul Tawab, Muhammad Irfan, Lubna Rajput, Imran Amin, Sumera Yasmin. (2021). Differential Root Exudation and Architecture for Improved Growth of Wheat Mediated by Phosphate Solubilizing Bacteria. Frontiers in Microbiology. 12: 744094. DOI: 10.3389/fmicb.2021.744094.
  15. Ata Ullah, Lutfur Rahman, Syed Zajif Hussain, Wasim Abbas, Abdul Tawab, Asim Jilani, Sadia Zafar Bajwa, Waheed S Khan, Rabia Riaz, Irshad Hussain, Asma Rehman. (2021). Mechanistic insight of dye degradation, using TiO2 anchored α-MnO2 nanorods as promising sunlight driven photocatalyst. Materials Science and Engineering: B. 271: 115257. DOI: 10.1016/j.mseb.2021.115257.
  16. Muhammad Qamar, Saeed Akhtar, Tariq Ismail, YUAN Ye, Naveed Ahmad, Abdul Tawab, Amir Ismail, Ross T Barnard, Matthew A Cooper, Mark AT Blaskovich, Zyta M Ziora. (2021). Syzygium cumini (L.), Skeels fruit extracts: in vitro and in vivo anti-inflammatory properties. Journal of Ethnopharmacology. 271: 113805. DOI: 10.1016/j.jep.2021.113805.
  17. Muhammad Sajjad Ahmad, Chen-Guang Liu, Muhammad Nawaz, Abdul Tawab, Xiaoqian Shen, Boxiong Shen, Muhammad Aamer Mehmood. (2021). Elucidating the pyrolysis reaction mechanism of Calotropis procera and analysis of pyrolysis products to evaluate its potential for bioenergy and chemicals. Bioresource Technology. 322: 124545.
  18. Abdul Tawab., Noor Akbar, Mujtaba Hasssan, Fazal-e-Habib, Aamir Ali, Moazur Rahman, Abdul Jabbar, Waqar Rauf, Mazhar Iqbal (2020). Mass spectrometric analysis of lipid A obtained from the lipopolysaccharide of Pasteurella multocida. RSC Advances. 10:30917-30933. DOI: 10.1039/D0RA05463A.
  19. Muhammad Wasim, Haq Nawaz Khan, Hina Ayesha, Abdul Tawab, Fazal e Habib, Muhammad Rafique Asi, Mazhar Iqbal, Fazli Rabbi Awan. (2020). High levels of blood glutamic acid and ornithine in children with intellectual disability. International Journal of Developmental Disabilities. 68(5):1-7. DOI: 10.1080/20473869.2020.1858520.
  20. Muhammad Qamar, Akhtar. S., Ismail. T., Sestili. P., Tawab. A., Ahmed. N. (2020). Anticancer and anti-inflammatory perspectives of Pakistan’s indigenous berry Grewia asiatica Linn (Phalsa). Journal of Berry Research. 10:115-131.
  21. Mehmood. A., Hussain. A., Irshad. M., Hamayun. M., Iqbal. A., Tawab. A., Khan. N. (2020). Yucasin and cinnamic acid inhibit IAA and flavonoids biosynthesis minimizing interaction between maize and endophyte Aspergillus nomius. Symbiosis. 81:149-160.
  22. Akbar, N., Khan, N. A., K Sagathevan, Iqbal, M., Tawab, A. and Siddiqui, R. (2019). Gut bacteria of Cuora amboinensis (turtle) produce broad-spectrum antibacterial molecules. Scientific Reports. 9(1):1-19. DOI: 10.1038/s41598-019-52738-w.
  23. Bibi. N., Jan. G., Jan. F. G., Hamayun. M., Iqbal. A., Hussain. A., Rehman. H., Tawab. A., Khushdil. F. (2019). Cochliobolus sp. acts as a biochemical modulator to alleviate salinity stress in okra plants. Plant Physiology and Biochemistry. 139: 459-469.
  24. Mehmood. A., Hussain. A., Irshad. M., Hamayun. M., Iqbal. A., Rahman. H., Tawab. A., Ahmad. A., Ayaz. S. (2019). Cinnamic acid as an inhibitor of growth, flavonoids exudation and endophytic fungus colonization in maize root. Plant Physiology and Biochemistry. 135: 61-68.
  25. Rahman. H., Khan. I., Hussain. A., Shahat. A. A., Tawab. A., Qasim. M., Adnan. M., Al-Said. M. S., Ullah. R., Khan. S. N., Welz. A. N., Emberger-Klein. A., Menrad. K. (2018). Herbal Medicine. Journal of the Australian Traditional-Medicine Society. 24:2, 113-115.
  26. Rahman. H., Khan. I., Hussain. A., Shahat. A. A., Tawab. A., Qasim. M., Adnan. A., Al-Said. M. S., Ullah. R., Khan. S. N. (2018). Glycyrrhiza glabra HPLC fractions: identification of Aldehydo Isoophiopogonone and Liquirtigenin having activity against multidrug resistant bacteria.  BMC complementary and alternative medicine. 18:1, 140.
  27. Imran. M., Habib. F., Majeed. S., Tawab. A., Rauf. W., Rahman. M., Umer. M., Iqbal. M. (2018). LC-MS/MS based determination of chloramphenicol, thiamphenicol, florfenicol and florfenicol amine in poultry meat from the Punjab-Pakistan. Food Additives & Contaminants: Part A. 35(8): 1530-1542. DOI: 10.1080/19440049.2018.1463569.
  28. Ahmad. M. S., Mehmood. M. A., Liu. C. G., Tawab. A., Bai. F. W., Sakdaronnarong. C., Xu. J., Rahimuddin. S. A., Gull. M. (2018). Bioenergy potential of Wolffia arrhiza appraised through pyrolysis, kinetics, thermodynamics parameters and TG-FTIR-MS study of the evolved gases. Bioresource Technology. 253: 297-303.
  29. Wasim. M., Awan. F. R., Khan. H. N., Tawab. A., Iqbal. M., Ayesha. H. (2017). Aminoacidopathies: Prevalence, Etiology, Screening, and Treatment Options. Biochemical Genetics. 56:7-21.
  30. Majeed. S., Boevre. M. D., Saeger. S. D., Rauf. W., Tawab. A., Rahman. M., Iqbal. M. (2018). Multiple Mycotoxins in Rice: Occurrence and Health Risk Assessment in Children and Adults of Punjab, Pakistan. Toxins. 10(2): 77.
  31. Ye. G, Luo. H., Ren. Z., Ahmad. M. S., Liu. C. G., Tawab. A., Al-Ghafari. A. B., Omar. U., Gull. M., Mehmood. M. A. (2018). Evaluating the bioenergy potential of Chinese Liquor-industry waste through pyrolysis, thermogravimetric, kinetics and evolved gas analyses. Energy Conversion and Management. 163: 13-21.
  32. Khan. I., Rahman. H., El-Salam.N. M. A., Tawab. A., Hussain. A., Khan. T. A., Khan. U. A., Qasim. M., Adnan. M., Azizullah., Murad. W., Jalal. A., Muhammad. N., Ullah. R. (2017). Punica granatum peel extracts: HPLC fractionation and LC MS analysis to quest compounds having activity against multidrug resistant bacteria. BMC Complementary and Alternative Medicines. 17:247.
  33. Imran. M., Habib. F., Tawab. A., Rauf. W., Rahman. M., Khan. Q. M., Asi. M. R., Iqbal. M. (2017). LC-MS/MS based method development for the analysis of florfenicol and its application to estimate relative distribution in various tissues of broiler chicken. Journal of Chromatography B. 1063: 163-173.
  34. Riaz. M., Rasool. N., Iqbal. M., Tawab. A., Habib. F., Khan. A., Farman. M. (2017). Liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) analysis of Russelia equisetiformis extract. Bulgharian Chemical Communications. 49 (2):354-359.
  35. Jabbar. A., Ali. A., Tawab. A., Haque. A., Iqbal. M. (2014). Fatty acid profiling of lipid-A isolated from indigenous Salmonella Typhi strain by gas chromatography–mass spectrometry. The Chemical Society of Pakistan. 36(1): 140-149.
  36. Naveed. R., Hussain. I., Tawab. A., Tariq. M., Rahman. M., Hameed. S., Mahmood. M. S., Siddique. A. B., Iqbal. M. (2013). Antimicrobial activity of the bioactive components of essential oils from Pakistani spices against Salmonella and other multi-drug resistant bacteria. BMC Complementary and Alternative Medicine. 13:265.
  37. Ghauri. M. A., Anwar. M. A., Akhtar. N., Haider. R., Tawab. A. (2009). Status of Coal Biotechnology in Pakistan. Advance Materials Research. 71-73: 513-516

 


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