Friday, April 19, 2024
Profile

Dr. Aamir Shehzad

dr.aamir.biotech@gmail.com


Senior Scientist


Cell/Direct Phone: +92 331 8894292

Qualifications:

  •             2013    Ph.D Biotechnology, RWTH Aachen University, Germany
  •             2010    M.Sc. Molecular Life Science, Jacobs University Bremen, Germany
  •             2006    B.Sc. (Hons.) Biotechnology, University of Peshawar, Pakistan

 

Research Interests:

Protein expression, protein purification, X-ray crystallography of proteins, protein-ligand interactions.

Crystal structures deposited in the Protein Data Bank (PDB):

  • 4HGF  Crystal structure of P450 BM3 5F5K heme domain variant complexed with styrene
  • 4HGG Crystal structure of P450 BM3 5F5R heme domain variant complexed with styrene
  • 4HGH Crystal structure of P450 BM3 5F5 heme domain variant complexed with styrene (dataset I)       
  • 4HGI   Crystal structure of P450 BM3 5F5 heme domain variant complexed with styrene (dataset II)     
  • 4HGJ   Crystal structure of P450 BM3 5F5 heme domain variant    
  • 5E78    Crystal structure of P450 BM3 heme domain variant complexed with Co(III)Sep
  • 5E7Y   Crystal structure of P450 BM3 heme domain M7 variant     

4. Publications: 

  • Saravanan Panneerselvam?*, Aamir Shehzad*, Jochen Mueller-Dieckmann?, Matthias Wilmanns?, Marco Bocola, Mehdi D. Davari?, and Ulrich Schwaneberg. (2018). Crystallographic insights into a cobalt (III) sepulchrate based alternative cofactor system of P450 BM3 monooxygenase. BBA - Proteins and Proteomics. Vol. 1866 (1), Pages 134-140.
  • Feng Cheng, Tsvetan Kardashliev, Christian Pitzler, Aamir Shehzad, Hongqi Lue, Jürgen Bernhagen, Leilei Zhu, and Ulrich Schwaneberg. (2015). A competitive flow cytometry screening system for directed evolution of therapeutic enzyme. ACS Synthetic Biology. Vol. 4 (7), Pages 768-775.
  • Aamir Shehzad*, Saravanan Panneerselvam*, Marina Linow, Marco Bocola, Danilo Roccatano, Jochen Mueller-Dieckmann, Matthias Wilmanns, and Ulrich Schwaneberg. (2013). P450 BM3 crystal structures reveal the role of the charged surface residue Lys/Arg184 in inversion of enantioselective styrene epoxidation. Chemical Communications. Vol. 49(41), Pages 4694-4696.
  • Astrid Gärdes, Eva Kaeppel, Aamir Shehzad, Shalin Seebah, Hanno Teeling, Pablo Yarza, Frank Oliver Glöckner, Hans-Peter Grossart, and Matthias S. Ullrich. (2010). Complete genome sequence of Marinobacter adhaerens type strain (HP15), a diatom-interacting marine microorganism. Standards in Genomic Sciences. Vol. 3(2), Pages 97-107.

   
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